You have full access to this article via your institution. One of the most widespread applications of the microarray technology is to perform expression profiling to compare levels of transcripts ...

Jonathan Weissman at the University of California, San Francisco wants to know how cells fold proteins into the right shapes, and he knocks down genes to find out. For that he uses massive RNA ...

From the synthetic biology FAQ: Current synthesis costs are about $1 per base pair. Current synthesis times for a 1,500 bp gene are of order 4 weeks. We need a ~3-fold reduction in cost ($0.33 for 3 ...

- The next frontier in oligonucleotide synthesis is the direct synthesis of gene-length sequences. - Ansa synthesized a 1005 base long oligonucleotide with industry-leading accuracy. - Ansa will be ...

Oligonucleotide-based drugs continue to flow into developmental pipelines, and the relatively large numbers now being tested in humans and progressing through late-stage clinical studies have buoyed ...