Using an informatics tool that identifies “hotspots” of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechanism that puts the brakes on an ...

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...