Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also ...

Leptin is a neurotransmitter that is produced in fat cells and is involved in appetite. Leptin works through the action of several small proteins called neuropeptides, such as thyrotopin-releasing ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

Research on young mice into leptin has suggested that the hormone can change their brains’ circuitry, creating permanent controls on their appetite, henceforth controlling obesity. According to a ...

WEIGHT CONTROL: Leptin might regulate body weight by signaling the size of the fatty tissue mass, research led by Jeffrey Friedman shows. M. Maffei, J. Haalas, E ...

Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...

Scientists have found that a midgestation increase in the hormone leptin, which most of us associate with appetite suppression, produces problematic blood vessel dysfunction and restriction of the ...