The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Surprisingly, forcing an acceleration of replication forks led to miscoordination between genome replication completion and cell cycle progression. Dr. Tsubouchi concludes, "We propose that slow ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

Researchers at the University of Illinois Urbana-Champaign have built a computer simulation that tracks the entire life cycle of a living cell in four dimensions, capturing how the genetically minimal ...

The herpesvirus can manipulate our DNA with far more precision than previously thought. The virus condenses and changes the shape of our genetic material to hijack the host genes needed for ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

DNA is often called the blueprint of life, but what does that really mean? Elizabeth Worthey, Ph.D., associate professor, Department of Genetics in the Heersink School of Medicine, explains everything ...