Intron retention is recognized as a key process in disease development, but its role in tuberculosis (TB) progression is ...

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global ...

We are far from understanding all the rules that govern the process of RNA splicing and defining the sequence information that governs intron definition. In the September 25 Proceedings of the ...

Shown is the splicing pathway. The pre-messenger RNA (pre-mRNA) has exons (blue) and introns (pink). The spliceosome (not shown) was known to catalyze two chemical reactions (black arrows) in a ...

Although the participation of spliceosomes is almost always required for intron removal, a few types of genes have self-splicing RNA introns. The RNA transcript of such a gene can carry out the entire ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...

The completed sequencing of entire bacterial genomes and recent advances in genomics has allowed the identification of many genes. While several genes have been characterized, the function of the ...