Matt Taylor is a senior process development associate at KBI Biopharma, where he focuses on the design, optimization, and scale-up of purification processes for biopharmaceutical manufacturing. Matt ...

The landscape of novel monoclonal antibody (mAb) therapeutic formats has expanded significantly in recent years, introducing new challenges in the purification process. Traditional full-length IgG ...

SOMERSET, N.J. & ST. PAUL, Minn.-- (BUSINESS WIRE)--Catalent Pharma Solutions and 3M Purification Inc., recently investigated a novel purification approach that significantly increased the performance ...

Antibodies are characterized by two functionally important regions, the Fab (two of which are present in a single antibody molecule) and the Fc, the former dictating target specificity and the latter ...

The growing complexity of antibody therapeutics has driven rapid innovation in downstream processing. As novel formats such as bispecifics, fragments and antibody–drug conjugates (ADCs) expand, so ...

At-line process monitoring (ALPM) is a major application of ultra-high performance size-exclusion chromatography (UHP-SEC). ALPM of biological drugs helps to reduce the time and effort associated with ...

The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with clarification and filtration playing significant roles. However, clogs, complex ...

Development of robust purification processes requires significant time and resources. In addition, steadily increasing demands from regulatory authorities for better understanding and control of ...

Raman spectroscopy is a non-destructive analysis technique that is outstanding for measuring the frequencies of chemical bond vibrations. As these occur at particular energies relying on the exact ...

The acquisition will add Belgium-based chromatography operations and a team of over 50 employees to Merck.