The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...

Researchers at UT Southwestern Medical Center at Dallas are the first to use genetically engineered mice containing a fluorescent molecule to examine in real time the chemical reactions that result in ...

We conclude that this type of model, in which the M3 reflection is solely due to the myosin heads, and all the myosin heads in the fibre respond to filament sliding, is incompatible with the observed ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...