The field of neuroplasticity is increasingly exploring the non-neuronal components that shape synaptic, cellular, and circuit-level adaptation in the brain.

Summary: For decades, scientists have known that the protein tau acts like a wildfire in the brain, leaping from region to region and leaving a trail of cognitive decline. Now, a decade-long study has ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or ...

The ability to measure the connectivity of each neuron in a neural circuit has established large maps of neuronal pathways—the connectome. But the extent to which those connectivity measurements alone ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Researchers at University of Tsukuba have identified a previously uncharacterized neural circuit that directly links emotional processing to arousal. In the pathway, GABAergic neurons in the bed ...

When defending their territory, male mice typically appear threatening before launching an attack, ensuring that aggression ...

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium ...