Explore essential statistical strategies for accurate protein quantification and differential expression analysis.

For biologists, DNA microarrays present at once unprecedented opportunities and monumental challenges. In the opportunities column, microarrays produce genome-wide gene expression snapshots, ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

Protein microarrays are many things to many people. Like the more mature DNA “chips”, they are often patterns of tiny spots arrayed on a microscope-type slide, used to determine the makeup and amount ...

In microarray gene expression experiments, several diverse conditions in each experiment (e.g., time, doses, replicates) increase the data points from tens of thousands of measurements for a single ...

This study aims to identify potential biomarkers of hepatocellular carcinoma (HCC) occurrence/recurrence and obesity, along with the molecular mechanisms that involve these biomarkers. Three ...

Autoimmune diseases that stem from an autoaggression of the immune system toward a subject's own tissues and organs still represent a field of intense research in the hope to identify why this occurs ...

It is necessary to identify such new genes as biomarkers to aim to early detection of HCC. In other words, it may assist us in more accurate prediction of the progression of HCC. In other words, a ...

As a graduate student, Eric Olson learned something about DNA microarrays: Biochip data management can be vexing. His graduate adviser abandoned a number of microarray experiments because it was too ...