The 3Rs (replacement, reduction, refinement) are a set of principles that provide an internationally accepted framework toward achieving more humane scientific research by minimizing animal distress.

The IACUC endorses the application of the 3 Rs ( Reduction, Replacement and Refinement) concept to the minimization of pain and distress in animals. Three Rs Presentation Multiple survival surgeries ...

The wages of inhumanity are paid in ambiguous or otherwise unsatisfactory experimental results. The authors introduce the concept of the 3 Rs, i.e. Replacement, Reduction, Refinement. Desirable as ...