Many biological functions and systems are influenced by how gene expression is spatially distributed, from subcellular through to tissue, organ, or at embryonic level. Our understanding of these ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Mapping biological networks in lung adenocarcinoma using transcriptomic analysis to identify prognostic biomarkers and therapeutic targets.

From startups to giants in pharma and tools, the use of spatial biology is growing in importance in drug discovery. LatchBio, a four-year-old San Francisco builder of software and data infrastructure ...

Neoadjuvant immunotherapy in combination with chemotherapy in resectable locally advanced head and neck squamous cell carcinoma: A randomized, open label, phase II clinical trial. This is an ASCO ...