A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can ...

Ciliates, a group of single-celled ciliated eukaryotes, have been studied since the dawn of light microscopy, with over 10,000 species described. Cilia are the key feature of ciliates and contribute ...

Immunoenzymatic chromogen staining is an immunology staining technique used to visually detect two or more antigenic markers within a single tissue sample (colocalization). With the help of chromogens ...

To ensure that the tissue structures of biological samples are easily recognisable under the electron microscope, they are treated with a staining agent. The standard staining agent for this is ...

In many cases, researchers are faced with the need to detect two or more antigens in a single tissue specimen. The creates an issue called ‘colocalization’, where an antibody binds to multiple ...

Microscopes have revolutionized the practice of science, especially in the fields of biology and medicine. Just a few hundred years ago, gaining the ability to study what was previously unobservable ...

Microscopes have been fine-tuned to image cells in granular detail, with the most sophisticated instruments capable of resolving individual atoms within a protein. The expense of microscopes creates ...

Sensing: point-of-care sensors, mobile-phone enabled sensors, field-based sensing and measurement systems with applications in mobile health and telemedicine, environmental monitoring (for example, ...

To date, examining patient tissue samples has meant cutting them into thin slices for histological analysis. This might now be set to change, thanks to a new staining method. This allows specialists ...