In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

Gene dysregulation is a hallmark of disease, driving pathogenic phenotypes and poor patient outcomes. RNA binding proteins are often important human gene effectors, controlling RNA synthesis, ...

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, ...

Figure 4. Structural effects of a single frameshift homozygous nucleotide deletion in the SPAG9/JIP4 gene. Representation of the three-dimensional model in tapes. (A) Region of the SPAG9wt protein ...

Researchers revealed a CRISPR system that activates gene expression rather than cutting DNA, using RNA-guided targeting. The ...