Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

The coronavirus disease 2019 (Covid-19) pandemic has highlighted the crucial role of randomized trials in guiding clinical practice and the need for designs that provide rapid evaluation of multiple ...

Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. We performed a pragmatic, randomized ...